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EP3 antagonist 2

EP3 antagonist 2 (Compound Exp 1) is a potent and selective EP3 receptor antagonist. EP3 antagonist 2 has a strong binding affinity for the human EP3 receptor (Ki: 3.3 nM) and significant antagonistic activity (IC50: 30.8 nM, determined by cellular cAMP levels) [1].

Product Specifications

CAS Number

1952261-87-8

UNSPSC

12352005

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Others

Smiles

O=C1C([C@]2(C)C(NCCC2)=O)=CC=C(C3=CC4=C(C)C=CC=C4N=C3)N1

Molecular Formula

C21H21N3O2

Molecular Weight

347.41

References & Citations

[1]Kevin Bahnck, et al. Antagonists of prostaglandin ep3 receptor. US20160176851A1. 2016-06-23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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