EP3 antagonist 2
EP3 antagonist 2 (Compound Exp 1) is a potent and selective EP3 receptor antagonist. EP3 antagonist 2 has a strong binding affinity for the human EP3 receptor (Ki: 3.3 nM) and significant antagonistic activity (IC50: 30.8 nM, determined by cellular cAMP levels) [1].
Product Specifications
CAS Number
[1952261-87-8]
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Others
Smiles
O=C1C([C@]2(C)C(NCCC2)=O)=CC=C(C3=CC4=C(C)C=CC=C4N=C3)N1
Molecular Formula
C21H21N3O2
Molecular Weight
347.41
References & Citations
[1]Kevin Bahnck, et al. Antagonists of prostaglandin ep3 receptor. US20160176851A1. 2016-06-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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