EP3 antagonist 2
EP3 antagonist 2 (Compound Exp 1) is a potent and selective EP3 receptor antagonist. EP3 antagonist 2 has a strong binding affinity for the human EP3 receptor (Ki: 3.3 nM) and significant antagonistic activity (IC50: 30.8 nM, determined by cellular cAMP levels) [1].
Product Specifications
CAS Number
1952261-87-8
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Others
Smiles
O=C1C([C@]2(C)C(NCCC2)=O)=CC=C(C3=CC4=C(C)C=CC=C4N=C3)N1
Molecular Formula
C21H21N3O2
Molecular Weight
347.41
References & Citations
[1]Kevin Bahnck, et al. Antagonists of prostaglandin ep3 receptor. US20160176851A1. 2016-06-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
C1234138 40 Reactions
cDNA - Human Adult Normal Tissue: Heart: Ventricle (left)
Sign In for Pricing
View Details GTR15377089 1 Vial
Lentiviral human PHAX sgRNA gene knockout kit - Lentiviral human PHAX sgRNA gene knockout kit (100)
Sign In for Pricing
View Details