Emtricitabine triphosphate (tetrasodium salt)

Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596) . However, Emtricitabine triphosphate ((-) -Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427), a nucleoside reverse transcriptase inhibitor, targeting to HIV and HBV[1].

Product Specifications

CAS Number

[1188407-46-6]

Product Name Alternative

(-) -Emtricitabine triphosphate (tetrasodium salt)

UNSPSC

12352005

Target

HBV; HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Concentration

100 mM * 174 μL in Water

Purity

99.20

Solubility

10 mM in DMSO

Smiles

O=P(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])OC[C@@H]1O[C@H](N2C=C(F)C(N)=NC2=O)CS1

Molecular Formula

C8H9FN3Na4O12P3S

Molecular Weight

575.11

References & Citations

[1]Frasca K, et al. Emtricitabine triphosphate in dried blood spots is a predictor of viral suppression in HIV infection and reflects short-term adherence to antiretroviral therapy. J Antimicrob Chemother. 2019 May 1;74 (5) :1395-1401.|[2]Bang LM, et al. Emtricitabine: an antiretroviral agent for HIV infection. Drugs. 2003;63 (22) :2413-24; discussion 2425-6.