Ara-UTP

Ara-UTP is a sugar-modified nucleotide triphosphate that deceives RNA polymerases and blocks chain extension.

Product Specifications

CAS Number

[60102-52-5]

Product Name Alternative

Ara-uridine triphosphate

UNSPSC

12352005

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Smiles

O=C(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)NC1=O

Molecular Formula

C9H15N2O15P3

Molecular Weight

484.14

References & Citations

[1]Yuan C, Goonetilleke EC, Unarta IC, Huang X. Incorporation efficiency and inhibition mechanism of 2'-substituted nucleotide analogs against SARS-CoV-2 RNA-dependent RNA polymerase. Phys Chem Chem Phys. 2021 Sep 22;23 (36) :20117-20128. doi: 10.1039/d1cp03049c. PMID: 34514487.