ZX-2401

ZX-2401 (Compound 98a) is a 1,3,5-Triazine-based analogue of Purine (HY-34431) . ZX-2401 has a significant antiviral activity against viruses of the Flaviviridae family, such as West Nile Virus (WNV), Hepatitis C (HCV), Yellow Fever Virus (YFV), Dengue Virus (DV), Bovine Viral Diarrhea Virus (BVDV) and Banzi Virus (BV) with EC90s of 0.6-10 μg/mL. ZX-2401 significantly reduces virus production with an EC90 of 3.3 mg/mL. ZX-2401 can be used for influenza infections research[1].

Product Specifications

CAS Number

[67410-65-5]

UNSPSC

12352005

Target

Dengue Virus; Flavivirus; HCV; Influenza Virus

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=CN3C2=NC(N)=NC3=O)O1

Molecular Formula

C10H13N5O5

Molecular Weight

283.24

References & Citations

[1]Lim FP, et al. 1,3,5-Triazine-based analogues of purine: from isosteres to privileged scaffolds in medicinal chemistry. Eur J Med Chem. 2014 Oct 6;85:371-90.