M3 mAChR agonist 1
M3 mAChR agonist 1 is an M3-preferring M3/M5 mAChR dual positive allosteric modulators (PAM) . M3 mAChR agonist 1 shows excellent subtype selectivity over other subtypes of mAChRs including M1, M2, and M4 mAChRs. M3 mAChR agonist 1 increases the contraction of isolated rat bladder strips by modulating the M3 muscarinic acetylcholine receptor, leading to enhanced signaling pathways. M3 mAChR agonist 1 can be used for the research of endocrinology[1].
Product Specifications
CAS Number
1624297-26-2
UNSPSC
12352005
Target
MAChR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC=C(OC)C(C(F)(F)F)=C4)=C(CN5[C@H](CC)CCC5)S3)=O)N=C2)CC1)O
Molecular Formula
C29H33F3N6O4S
Molecular Weight
618.67
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR3; mAChR5
Frequently Asked Questions
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