Nor-Acetildenafil-d8

Nor-Acetildenafil-d8 is the deuterium labeled Nor-Acetildenafil. Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor[1].

Product Specifications

CAS Number

[1185117-07-0]

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

CCCC1=NN(C)C2=C1NC(C3=C(C=CC(C(CN4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C)=O)=C3)OCC)=NC2=O

Molecular Formula

C24H24D8N6O3

Molecular Weight

460.60

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Samuel R Gratz, et al. Accurate Mass Measurement Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Structure Elucidation of Designer Drug Analogs of Tadalafil, Vardenafil and Sildenafil in Herbal and Pharmaceutical Matrices. Rapid Commun Mass Spectrom. 2006;20 (15) :2317-27.