Nor-Acetildenafil-d8
Nor-Acetildenafil-d8 is the deuterium labeled Nor-Acetildenafil. Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor[1].
Product Specifications
CAS Number
1185117-07-0
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
CCCC1=NN(C)C2=C1NC(C3=C(C=CC(C(CN4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C)=O)=C3)OCC)=NC2=O
Molecular Formula
C24H24D8N6O3
Molecular Weight
460.60
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Samuel R Gratz, et al. Accurate Mass Measurement Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Structure Elucidation of Designer Drug Analogs of Tadalafil, Vardenafil and Sildenafil in Herbal and Pharmaceutical Matrices. Rapid Commun Mass Spectrom. 2006;20 (15) :2317-27.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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