(S) -MCOPPB

(S) -MCOPPB is the S-form of MCOPPB (HY-13101) . MCOPPB is an orally active and selective agonist of Nociceptin/Orphanin FQ-Receptor. MCOPPB inhibits signaling through the NOP receptor in the mouse brain. MCOPPB can be used for anxiety disorders study[1].

Product Specifications

CAS Number

[1108147-70-1]

UNSPSC

12352005

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

98.97

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1(CCCCCCC1)N2CCC(CC2)N3C([C@H]4CCCNC4)=NC5=CC=CC=C53

Molecular Formula

C26H40N4

Molecular Weight

408.62

References & Citations

[1]Hayashi S, et al. Novel non-peptide nociceptin/orphanin FQ receptor agonist, 1-[1- (1-Methylcyclooctyl) -4-piperidinyl]-2-[ (3R) -3-piperidinyl]-1H-benzimidazole: design, synthesis, and structure-activity relationship of oral receptor occupancy in the brain for orally potent antianxiety drug. J Med Chem. 2009 Feb 12;52 (3) :610-25.