Cobimetinib (racemate) (Standard)

Cobimetinib (racemate) (Standard) is the analytical standard of Cobimetinib (racemate) . This product is intended for research and analytical applications. Cobimetinib racemate (GDC-0973 racemate; XL518 racemate) is the racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor.

Product Specifications

CAS Number

[934662-91-6]

UNSPSC

12352100

Target

MEK; Reference Standards

Related Pathways

MAPK/ERK Pathway; Others

Field of Research

Cancer

Smiles

O=C(C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2F)N3CC(C4NCCCC4)(O)C3

Molecular Formula

C21H21F3IN3O2

Molecular Weight

531.31

References & Citations

[1]Hoeflich KP, et al. Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition. Cancer Res. 2012 Jan 1;72 (1) :210-9.