Celastrol (GMP)
Celastrol (GMP) (Tripterine (GMP) ) is Celastrol produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Celastrol (Tripterine; Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH[1][2][3].
Product Specifications
CAS Number
34157-83-0
Product Name Alternative
Tripterine (GMP) ; Tripterin (GMP)
UNSPSC
12352211
Target
Antibiotic; Apoptosis; Autophagy; Bacterial; Endogenous Metabolite; Mitophagy; Proteasome
Related Pathways
Anti-infection; Apoptosis; Autophagy; Metabolic Enzyme/Protease
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
OC1=C(C2=CC=C3[C@](C)([C@]4(CC[C@]3(C2=CC1=O)C)C)CC[C@@]5(C)CC[C@@](C(O)=O)(C[C@]54[H])C)C
Molecular Formula
C29H38O4
Molecular Weight
450.61
References & Citations
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Frequently Asked Questions
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