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VHC-7

VHC-7 is a potent and selective adenylyl cyclase type 8 (AC8) agonist, with an EC50 value of 105.2 nM. VHC-7 increases cyclic adenosine monophosphate (cAMP) levels. VHC-7 can be used for the study of central nervous system disorders and heart diseases[1].

Product Specifications

CAS Number

14750-21-1

UNSPSC

12352005

Target

Adenylate Cyclase

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Smiles

O=C(C1(CC2=CC=C(Cl)C=C2Cl)C(NC3=C1C=CC=C3)=O)OCC

Molecular Formula

C18H15Cl2NO3

Molecular Weight

364.22

References & Citations

[1]Weng Z, et al. Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening. Bioorg Med Chem Lett. 2020 Jan 15;30 (2) :126823.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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