VHC-7
VHC-7 is a potent and selective adenylyl cyclase type 8 (AC8) agonist, with an EC50 value of 105.2 nM. VHC-7 increases cyclic adenosine monophosphate (cAMP) levels. VHC-7 can be used for the study of central nervous system disorders and heart diseases[1].
Product Specifications
CAS Number
[14750-21-1]
UNSPSC
12352005
Target
Adenylate Cyclase
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Smiles
O=C(C1(CC2=CC=C(Cl)C=C2Cl)C(NC3=C1C=CC=C3)=O)OCC
Molecular Formula
C18H15Cl2NO3
Molecular Weight
364.22
References & Citations
[1]Weng Z, et al. Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening. Bioorg Med Chem Lett. 2020 Jan 15;30 (2) :126823.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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