Fostamatinib (disodium hexahydrate) (Standard)
Fostamatinib (disodium hexahydrate) (Standard) is the analytical standard of Fostamatinib (disodium hexahydrate) . This product is intended for research and analytical applications. Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406[1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM[2]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) [3].
Product Specifications
CAS Number
914295-16-2
UNSPSC
12352100
Target
FLT3; Reference Standards; Syk
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Inflammation/Immunology
Smiles
COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O[Na])(O[Na])=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC.O.O.O.O.O.O
Molecular Formula
C23H36FN6Na2O15P
Molecular Weight
732.51
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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