HQNO (Standard)
HQNO (Standard) is the analytical standard of HQNO. This product is intended for research and analytical applications. HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2].
Product Specifications
CAS Number
341-88-8
UNSPSC
12352005
Target
Mitochondrial Metabolism; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Infection
Smiles
OC(C1=C2C=CC=C1)=CC(CCCCCCC)=N2=O
Molecular Formula
C16H21NO2
Molecular Weight
259.34
References & Citations
[1]N J Jacobs, et al. Evidence for Involvement of the Electron Transport System at a Late Step of Anaerobic Microbial Heme Synthesis. Biochim Biophys Acta. 1977 Jan 6;459 (1) :141-4.|[2]Jessica Petri, et al. Structure of the NDH-2 - HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors. Biochim Biophys Acta Bioenerg. 2018 Jul;1859 (7) :482-490.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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