AZD6642
AZD6642 is a 5-lipoxygenase activating protein (FLAP) inhibitor. AZD6642 can effectively inhibit the production of LTB4. AZD6642 exhibits high oral bioavailability in rats and dogs. AZD6642 can be used in the research of inflammatory diseases[1].
Product Specifications
CAS Number
1643809-54-4
UNSPSC
12352005
Target
FLAP; Leukotriene Receptor
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
CC(C)(O)CNC(C1=NC=C([C@]2(C3=CC=C(C4=NC=C(N)N=C4)C=C3)CCCO2)C=C1)=O
Molecular Formula
C24H27N5O3
Molecular Weight
433.50
References & Citations
[1]Lemurell M, et al. Discovery of AZD6642, an inhibitor of 5-lipoxygenase activating protein (FLAP) for the treatment of inflammatory diseases. J Med Chem. 2015 Jan 22;58 (2) :897-911.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTB4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
