LY-228729
LY-228729 is a selective 5-HT1A receptor agonist. LY-228729 can reduce the rearing frequency of rats and decrease their activity in the central area in the open field test. LY-228729 can reduce the immobility time of rats and increase their swimming time in the forced swim test. LY-228729 can be used in the research of neurological diseases[1].
Product Specifications
CAS Number
115994-31-5
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
NC(C1=CC=C2NC=C3C2=C1C[C@@H](N(CCC)CCC)C3)=O
Molecular Formula
C18H25N3O
Molecular Weight
299.41
References & Citations
[1]Cannizzaro C, et al. Perinatal exposure to 5-methoxytryptamine, behavioural-stress reactivity and functional response of 5-HT1A receptors in the adolescent rat. Behav Brain Res. 2008 Jan 10;186 (1) :98-106.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor
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