L-367773
L-367773 is an orally active, selective oxytocin receptor antagonist, with Ki values of 26 nM and 61 nM for rat uterine oxytocin receptor and human uterine oxytocin receptor, respectively. L-367773 inhibits Oxytocin-stimulated uterine contractions[1].
Product Specifications
CAS Number
[152140-41-5]
UNSPSC
12352005
Target
Oxytocin Receptor
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Smiles
O=C(N[C@@H]1[C@](C2(C)C)(CS(=O)(N3CCC4(CC3)CCC5=C4C=CC=C5)=O)CC[C@]2([H])C1)CC6=CNC=N6
Molecular Formula
C28H38N4O3S
Molecular Weight
510.69
References & Citations
[1]Evans BE, et al. Nanomolar-affinity, non-peptide oxytocin receptor antagonists. J Med Chem. 1993 Dec 10;36 (25) :3993-4005.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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