DC-015

DC-015 is a selective and orally active alpha 1-adrenoceptor antagonist on plasma lipid and vascular reactivity in hyperlipidaemic rodent model. DC-015 is a synthesized quinazoline derivative. DC-015 decreases mean arterial pressure in rats. DC-015 has antihypertensive activity[1].

Product Specifications

CAS Number

[149847-87-0]

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

O=C1NC2=C(C=CC=C2)C3=NCC(CN4CCN(C5=CC=CC=C5OC)CC4)N13

Molecular Formula

C22H25N5O2

Molecular Weight

391.47

References & Citations

[1]Sheu, J. R., et al., (1996) . Effects of DC-015, a novel potent and selective alpha 1-adrenoceptor antagonist on plasma lipid and vascular reactivity in hyperlipidaemic rats. Clinical and experimental pharmacology & physiology, 23 (3), 207-213.