NU1064 (dihydrochloride)
NU1064 (dihydrochloride) is an inhibitor of PARP. NU1064 (dihydrochloride) potentiates the cytotoxicity of DNA-methylating agent (MTIC) in a concentration-dependent manner[1].
Product Specifications
CAS Number
[63916-38-1]
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Others
Smiles
O=C(C)OC1(CCN(CC1)CCCC)CC2=NC=CC=C2.Cl.Cl
Molecular Formula
C17H28Cl2N2O2
Molecular Weight
363.32
References & Citations
[1]Bowman, K. J., et al., (1998) . Potentiation of anti-cancer agent cytotoxicity by the potent poly (ADP-ribose) polymerase inhibitors NU1025 and NU1064. British journal of cancer, 78 (10), 1269-1277.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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