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PIN1 inhibitor 5

PIN1 inhibitor 5 (compound 7) is a PIN1 inhibitor (Ki=0.08 μM), which can be used in cancer research[1].

Product Specifications

CAS Number

[884033-66-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PIN1

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C([C@@H](CC1=NC2=CC=C(C=C2N1)F)NC(C3=CC=C4C=CC=CC4=C3)=O)O

Molecular Formula

C21H16FN3O3

Molecular Weight

377.37

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Chuangxing Guo, et al. Structure-based design of novel human Pin1 inhibitors (III) : optimizing affinity beyond the phosphate recognition pocket. Bioorg Med Chem Lett. 2014 Sep 1;24 (17) :4187-91.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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