Gilvocarcin M
Gilvocarcin M is an antibiotic and can be isolated from S. gilvotanareus. Gilvocarcin M is active against S. aureus at a concentration of 32 µg/ml and inhibits growth of KB cells with the IC50 of 0.52 µg/ml. Gilvocarcin M intercalates into bacteriophage PM2 DNA[1][2][3][4].
Product Specifications
CAS Number
77879-89-1
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Inflammation/Immunology
Smiles
O=C1C2=CC(C)=CC(OC)=C2C3=CC(OC)=C4C(O)=CC=C([C@@H]5[C@@H]([C@H]([C@H]([C@@H](C)O)O5)O)O)C4=C3O1
Molecular Formula
C26H26O9
Molecular Weight
482.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]Nakano H, et al. Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo) . 1981;34 (3) :266-270. |[2]Morimoto M, et al. Gilvocarcins, new antitumor antibiotics. 3. Antitumor activity. J Antibiot (Tokyo) . 1981;34 (6) :701-707.|[3]Tomita F, et al. Gilvocarcins, new antitumor antibiotics. 4. Mode of action. J Antibiot (Tokyo) . 1982 Aug;35 (8) :1038-41.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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