Gilvocarcin M

Gilvocarcin M is an antibiotic and can be isolated from S. gilvotanareus. Gilvocarcin M is active against S. aureus at a concentration of 32 µg/ml and inhibits growth of KB cells with the IC50 of 0.52 µg/ml. Gilvocarcin M intercalates into bacteriophage PM2 DNA[1][2][3][4].

Product Specifications

CAS Number

[77879-89-1]

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Inflammation/Immunology

Smiles

O=C1C2=CC(C)=CC(OC)=C2C3=CC(OC)=C4C(O)=CC=C([C@@H]5[C@@H]([C@H]([C@H]([C@@H](C)O)O5)O)O)C4=C3O1

Molecular Formula

C26H26O9

Molecular Weight

482.48

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Nakano H, et al. Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo) . 1981;34 (3) :266-270. |[2]Morimoto M, et al. Gilvocarcins, new antitumor antibiotics. 3. Antitumor activity. J Antibiot (Tokyo) . 1981;34 (6) :701-707.|[3]Tomita F, et al. Gilvocarcins, new antitumor antibiotics. 4. Mode of action. J Antibiot (Tokyo) . 1982 Aug;35 (8) :1038-41.