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JMV 3008

JMV 3008 is a GHS-R1a antagonist with an IC50 of 5.6 nM. JMV 3008 can be used in the research of diseases such as diabetes and obesity[1].

Product Specifications

CAS Number

925239-09-4

UNSPSC

12352005

Target

GHSR

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease

Smiles

O=C([C@H]1NCCC1)N[C@@H](C2=NN=C(CCC3=CNC4=C3C=CC=C4)N2CC5=CC=C(OC)C=C5OC)CC6=CNC7=C6C=CC=C7

Molecular Formula

C36H39N7O3

Molecular Weight

617.74

References & Citations

[1]Hanrahan P, et al. Substituted azaquinazolinones as modulators of GHSr-1a for the treatment of type II diabetes and obesity. Bioorg Med Chem Lett. 2012 Mar 15;22 (6) :2271-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GHSR1a

Frequently Asked Questions

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