XS018661
XS018661 is a dual inhibitor of the YEATS domains of ENL and its paralog AF9 with IC50 values of 1.6 and 3 μM as well as Kd values of 754 nM and 523 nM, respectively[1].
Product Specifications
CAS Number
878415-59-9
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(OC)C1=CC=C(C=C1)C(=O)NC=2C=CC=3N=C(NC3C2)CN4CCCCC4
Molecular Formula
C22H24N4O3
Molecular Weight
392.46
References & Citations
[1]Christott T, et al., Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9. SLAS Discov. 2019 Feb;24 (2) :133-141.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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