5-Methyl cromolyn (disodium)
5-Methyl cromolyn (C5OH) disodium, an analog of Cromolyn , is a S100P inhibitor. 5-Methyl cromolyn disodium inhibits the binding of S100P to its receptor RAGE, NF-κB activity and cell proliferation, and promotes Gemcitabine (HY-17026) -induced apoptosis. 5-Methyl cromolyn disodium reduces tumor growth and metastasis, and prolongs survival in mouse models of syngeneic PDAC. 5-Methyl cromolyn disodium can be used for pancreatic cancer like pancreatic ductal adenocarcinoma (PDAC) research[1].
Product Specifications
CAS Number
1221154-42-2
Product Name Alternative
C5OH
UNSPSC
12352005
Target
Apoptosis; Drug Derivative; NF-κB
Related Pathways
Apoptosis; NF-κB; Others
Field of Research
Cancer
Smiles
O=C(C(OC1=CC=CC(OCCC(CCOC(C=CC=C2OC(C(O[Na])=O)=C3)=C2C3=O)O)=C14)=CC4=O)O[Na]
Molecular Formula
C25H18Na2O11
Molecular Weight
540.38
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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