Glycyl-Exatecan (TFA)
Glycyl-Exatecan TFA (Glycyl-DX-8951 TFA), a derivative of Exatecan , is an anticancer agent. Glycyl-Exatecan TFA has significantly antitumor activity. Glycyl-Exatecan TFA can be used for cancers like solid tumors research[1].
Product Specifications
CAS Number
1883333-57-0
Product Name Alternative
Glycyl-DX-8951 (TFA) ; Exatecan analog 2 (TFA)
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.37
Solubility
DMSO : 100 mg/mL
Smiles
O=C(N[C@H]1CCC2=C3C1=C(CN4C(C(COC([C@@]5(CC)O)=O)=C5C=C46)=O)C6=NC3=CC(F)=C2C)CN.O=C(O)C(F)(F)F
Molecular Formula
C28H26F4N4O7
Molecular Weight
606.52
References & Citations
[1]Wente MN, et al. DE-310, a macromolecular prodrug of the topoisomerase-I-inhibitor exatecan (DX-8951), in patients with operable solid tumors. Invest New Drugs. 2005 Aug;23 (4) :339-47.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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