Docebenone (Standard)
Docebenone (Standard) is the analytical standard of Docebenone. This product is intended for research and analytical applications. Docebenone (AA 861) is a potent, selective and orally active 5-LO (5-lipoxygenase) inhibitor.
Product Specifications
CAS Number
[80809-81-0]
UNSPSC
12352100
Target
Ferroptosis; Lipoxygenase; Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
O=C1C(CCCCC#CCCCC#CCO)=C(C)C(C(C)=C1C)=O
Molecular Formula
C21H26O3
Molecular Weight
326.43
References & Citations
[1]Nam YH, et al. Leukotriene B (4) receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginalis-derived secretory products. Inflamm Res. 2012 Feb;61 (2) :97-102.|[2]Huang JK, et al. AA-861-induced Ca (2+) mobilization in Madin Darby canine kidney cells. Toxicol Appl Pharmacol. 1999 Dec 1;161 (2) :202-8.|[3]Kiriyama M, et al. Protective effect of AA-861 (5-lipoxygenase inhibitor) on experimental acute necrotizing pancreatitis in rats. Int J Pancreatol. 1993 Jun;13 (3) :201-8.|[4]Yamamura H, et al. Effect of AA-861, a selective 5-lipoxygenase inhibitor, on models of allergy in several species. Jpn J Pharmacol. 1988 Jul;47 (3) :261-71.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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