Sepetaprost

Sepetaprost (ONO-9054) is a dual agonist of prostaglandin E3 receptor and prostaglandin F receptor. Sepetaprost can reduce intraocular pressure and can be used for the researches of ocular hypertension and open angle glaucoma[1].

Product Specifications

CAS Number

[1262873-06-2]

Product Name Alternative

ONO-9054

UNSPSC

12352005

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Smiles

O=C(OC(C)C)CCC[C@H]1CC[C@@]([C@@H](/C=C/[C@@H](O)COC2=CC(F)=CC=C2F)[C@H](O)C3)([H])[C@@]3([H])OC1

Molecular Formula

C26H36F2O6

Molecular Weight

482.56

References & Citations

[1]Suto F, et al. A Novel Dual Agonist of EP3 and FP Receptors for OAG and OHT: Safety, Pharmacokinetics, and Pharmacodynamics of ONO-9054 in Healthy Volunteers. Invest Ophthalmol Vis Sci. 2015 Dec;56 (13) :7963-70.