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Colterol (hydrochloride)

Colterol hydrochloride is the hydrochloride salt form of Colterol. Colterol hydrochloride is the agonist for adrenergic receptor, and exhibits good affinity to β1-adrenoreceptor (heart) and β2-adrenoreceptor (lung) with IC50 of 645 nM and 147 nM. Colterol hydrochloride exhibits potential as a bronchodilator[1][2].

Product Specifications

CAS Number

52872-37-4

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cardiovascular Disease

Smiles

OC1=CC=C(C=C1O)C(CNC(C)(C)C)O.Cl

Molecular Formula

C12H20ClNO3

Molecular Weight

261.75

References & Citations

[1]Kusayama T, et al., Binding of a catechol derivative of denopamine (T-0509) and N-tert-butylnoradrenaline (Colterol) to beta 1- and beta 2-adrenoceptors. Biol Pharm Bull. 1994 Aug;17 (8) :1023-7. |[2]Kusayama T, et al., Binding of a catechol derivative of denopamine (T-0509) and N-tert-butylnoradrenaline (Colterol) to beta 1- and beta 2-adrenoceptors. Biol Pharm Bull. 1994 Aug;17 (8) :1023-7. |[3]Walker SB, et al., Bitolterol mesylate: a beta-adrenergic agent. Chemistry, pharmacokinetics, pharmacodynamics, adverse effects and clinical efficacy in asthma. Pharmacotherapy. 1985 May-Jun;5 (3) :127-37.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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