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KRAS G12C-IN-72

KRAS G12C-IN-72 (Example 571) is a KRAS G12C inhibitor. KRAS G12C-IN-72 can be used as a target protein ligand to synthesize PROTACs, such as KRAS degrader-1. KRAS G12C-IN-72 can be used in cancer research[1].

Product Specifications

CAS Number

2326523-41-3

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; Ras

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway; PROTAC

Field of Research

Cancer

Smiles

ClC1=CC=CC2=C1C(N3CC4=NC(OC[C@@H]5CCCN5)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C4CC3)=CC=C2

Molecular Formula

C31H33ClFN7O2

Molecular Weight

590.09

References & Citations

[1]James F. Blake, et al. Kras g12c inhibitors. US20190144444A1. United States. 2018-11-14.

Shipping Conditions

Room temperature

Scientific Category

Reference compound

Clinical Information

No Development Reported

Isoform

K-Ras

Frequently Asked Questions

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