C20-Dihydrosphingomyelin
C20-Dihydrosphingomyelin (C20-DHSM; DHSM (d18:0/20:0) ) is a saturated form of Sphingomyelin. C20-Dihydrosphingomyelin is a secondary component of most cell sphingolipids and its levels significantly decrease after intermittent fasting during Ramadan. C20-Dihydrosphingomyelin can be used for the development of liposome reagents[1][2][3].
Product Specifications
CAS Number
917104-47-3
Product Name Alternative
C20-DHSM; DHSM (d18:0/20:0)
UNSPSC
12352211
Target
Endogenous Metabolite; Liposome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
CCCCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)CCCCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O
Molecular Formula
C43H89N2O6P
Molecular Weight
761.15
References & Citations
[1]Madkour MI, et al. Ramadan intermittent fasting is associated with ameliorated inflammatory markers and improved plasma sphingolipids/ceramides in subjects with obesity: lipidomics analysis. Sci Rep. 2023 Oct 13;13 (1) :17322.|[2]Kasagi N, et al. Optimization of dihydrosphingomyelin/cholesterol mol ratio in topotecan-loaded liposomes to enhance drug retention and plasma half-life by understanding physicochemical and thermodynamic properties of the lipid membrane. Journal of Molecular Structure. 2023 Jul 5;1283:135333.|[3]Yano M, et al. Quantitative analysis of ceramide molecular species by high performance liquid chromatography. J Lipid Res. 1998 Oct;39 (10) :2091-8. PMID: 9788256.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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