HCV-IN-50
HCV-IN-50 (Compound 2) is a competitive and selective HCV NS5B RNA-dependent RNA polymerase inhibitor with an IC50 of 0.3 μM for NS5B △C21 enzyme over △C55 enzyme. HCV-IN-50 has an antiviral activity and efficiently blocks replication of HCV subgenomic replicons especially mutant replicons[1].
Product Specifications
CAS Number
[303776-85-4]
UNSPSC
12352005
Target
DNA/RNA Synthesis; HCV Protease
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C1N(CC(C)C)C2=C(C=CC=C2)C(O)=C1C(NC3=CC=CC=C34)=NS4(=O)=O
Molecular Formula
C20H19N3O4S
Molecular Weight
397.45
References & Citations
[1]Tomei L, et al. Characterization of the inhibition of hepatitis C virus RNA replication by nonnucleosides. J Virol. 2004 Jan;78 (2) :938-46.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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