β-CCM

β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and proconvulsant effects. β-CCM enhances emotional reactivity and reduces vulnerability to interference in spatial working memory tasks. β-CCM can be used for research on anxiety-related disorders[1][2].

Product Specifications

CAS Number

[69954-48-9]

Product Name Alternative

Beta-CCM; Ro 22-7497

UNSPSC

12352005

Hazard Statement

H302-H312-H315-H319-H332-H335

Target

GABA Receptor

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Purity

98.95

Smiles

O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)OC

Molecular Formula

C13H10N2O2

Molecular Weight

226.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Krazem A, et al. Effects of diazepam and beta-CCM on working memory in mice: relationships with emotional reactivity. Pharmacol Biochem Behav. 2001 Feb;68 (2) :235-44. |[2]Chapouthier, G., et al. Comparison between the effects of the benzodiazepine receptor ligands methyl beta-carboline-3-carboxylate and diazepam in two learning situations in mice. Psychobiology 19, 58–63 (1991) .