MCC950 (Standard)
MCC950 (Standard) is the analytical standard of MCC950. This product is intended for research and analytical applications. MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
Product Specifications
CAS Number
[210826-40-7]
UNSPSC
12352100
Target
NOD-like Receptor (NLR) ; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
O=S(C1=CC(C(C)(O)C)=CO1)(NC(NC2=C3CCCC3=CC4=C2CCC4)=O)=O
Molecular Formula
C20H24N2O5S
Molecular Weight
404.48
References & Citations
[1]Coll RC, et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. 2015 Mar;21 (3) :248-55.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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