B-TPMF
B-TPMF is a selective inhibitor of the KCa2.1 channel, with an IC50 of 30 nM, and it has a competitive functional interaction with CM-TPMF[1].
Product Specifications
CAS Number
477865-65-9
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Smiles
CON/C=N/C1=NN2C(C(OC3=CC=C(C(C)(C)C)C=C3)C)=CC=NC2=N1
Molecular Formula
C19H24N6O2
Molecular Weight
368.43
References & Citations
[1]Charlotte Hougaard, et al. Evidence for a common pharmacological interaction site on K (Ca) 2 channels providing both selective activation and selective inhibition of the human K (Ca) 2.1 subtype. Mol Pharmacol. 2012 Feb;81 (2) :210-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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