B-TPMF

B-TPMF is a selective inhibitor of the KCa2.1 channel, with an IC50 of 30 nM, and it has a competitive functional interaction with CM-TPMF[1].

Product Specifications

CAS Number

[477865-65-9]

UNSPSC

12352005

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cardiovascular Disease

Smiles

CON/C=N/C1=NN2C(C(OC3=CC=C(C(C)(C)C)C=C3)C)=CC=NC2=N1

Molecular Formula

C19H24N6O2

Molecular Weight

368.43

References & Citations

[1]Charlotte Hougaard, et al. Evidence for a common pharmacological interaction site on K (Ca) 2 channels providing both selective activation and selective inhibition of the human K (Ca) 2.1 subtype. Mol Pharmacol. 2012 Feb;81 (2) :210-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MF-0044636-01 100 mg

Apoarantoin

Ask

View Details

MF-0044636-02 25 mg

Apoarantoin

Ask

View Details

MF-0044636-03 50 mg

Apoarantoin

Ask

View Details

A15550-25 25 mg

CCT244747 25mg

Ask

View Details

NBP2-74585AF488 0.1 mL

Mouse Monoclonal Transketolase Antibody (OTI5H3) [Alexa Fluor 488]

Ask

View Details

MBS9019218-01 0.05 mL

TROP2 Recombinant Monoclonal Antibody

Ask

View Details