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ML171 (Standard)

ML171 (Standard) is the analytical standard of ML171. This product is intended for research and analytical applications. ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay.

Product Specifications

CAS Number

6631-94-3

UNSPSC

12352100

Hazard Statement

H302, H412

Target

NADPH Oxidase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Purity

98.62

Smiles

CC(C1=CC=C2SC3=CC=CC=C3NC2=C1)=O

Molecular Formula

C14H11NOS

Molecular Weight

241.31

Precautions

H302, H412

References & Citations

[1]Gianni D, et al. A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. ACS Chem Biol. 2010 Oct 15;5 (10) :981-93.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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