VAS2870 (Standard)

VAS2870 (Standard) is the analytical standard of VAS2870. This product is intended for research and analytical applications. VAS2870 is a NADPH oxidase (NOX) inhibitor.

Product Specifications

CAS Number

[722456-31-7]

UNSPSC

12352100

Target

NADPH Oxidase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Smiles

C1(N(CC2=CC=CC=C2)N=N3)=C3C(SC4=NC5=C(C=CC=C5)O4)=NC=N1

Molecular Formula

C18H12N6OS

Molecular Weight

360.39

References & Citations

[1]ten Freyhaus H, et al. Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation. Cardiovasc Res. 2006 Jul 15;71 (2) :331-41.|[2]Sancho P, et al. The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells. Biochem Pharmacol. 2011 Apr 1;81 (7) :917-24.