VHR-IN-1
VHR-IN-1 (Compound SA1) is a potent and selective VHR phosphatase inhibitor with an IC50 of 18 nM. VHR-IN-1 can inhibit the proliferation of cervix cancer cells and has anti-tumor activity[1].
Product Specifications
CAS Number
[956189-91-6]
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=S(CCN(C/1=O)C(SC1=C/C2=CN(C3=CC=CC=C3)N=C2C4=CC=C(OCC5=CC=C(Cl)C=C5)C=C4)=S)(O)=O
Molecular Formula
C28H22ClN3O5S3
Molecular Weight
612.14
References & Citations
[1]Wu S, et al. Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells. J Med Chem. 2009 Nov 12;52 (21) :6716-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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