Etrasimod (Standard)
Etrasimod (Standard) is the analytical standard of Etrasimod. This product is intended for research and analytical applications. Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an IC50 value of 1.88 nM in CHO cells.
Product Specifications
CAS Number
1206123-37-6
UNSPSC
12352100
Target
LPL Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Inflammation/Immunology
Smiles
FC(F)(F)C1=CC(COC2=CC=C(NC3=C4CC[C@@H]3CC(O)=O)C4=C2)=CC=C1C5CCCC5
Molecular Formula
C26H26F3NO3
Molecular Weight
457.48
References & Citations
[1]Buzard DJ, et al. Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor. ACS Med Chem Lett. 2014 Nov 4;5 (12) :1313-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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