Hydroxy Itraconazole-d6
Hydroxy Itraconazole-d6 (R-63373-d6) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
Product Specifications
Product Name Alternative
R-63373-d6
UNSPSC
12352005
Target
Fungal; Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Others
Smiles
O=C1N(C(C([2H])(C([2H])([2H])[2H])O)([2H])C)N=C([2H])N1C2=CC=C(N3CCN(CC3)C4=CC=C(C=C4)OCC5OC(C6=CC=C(C=C6Cl)Cl)(CN7N=CN=C7)OC5)C=C2
Molecular Formula
C35H32D6Cl2N8O5
Molecular Weight
727.67
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Mino Y, et al. Hydroxy-itraconazole pharmacokinetics is similar to that of itraconazole in immunocompromised patients receiving oral solution of itraconazole. Clin Chim Acta. 2013 Jan 16;415:128-32.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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