Mebeverine acid-d3

Mebeverine acid-d3 (Mebeverine metabolite Mebeverine acid-d3) is the deuterium labeled Mebeverine Acid (HY-12769) . Mebeverine acid is a secondary metabolite of the intestinal antispasmodic agent Mebeverine (HY-A0078) . Mebeverine acid is generated by the hydrolysis of Mebeverine in the body and is considered a key circulating metabolite. Mebeverine acid is an important marker for oral Mebeverine.

Product Specifications

Product Name Alternative

Mebeverine metabolite Mebeverine acid-d3

UNSPSC

12352211

Target

Drug Derivative; Isotope-Labeled Compounds

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(CCCN(C(CC1=CC=C(C=C1)OC([2H])([2H])[2H])C)CC)O

Molecular Formula

C16H22D3NO3

Molecular Weight

282.39

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Arnel Stockis, et al. Identification of mebeverine acid as the main circulating metabolite of mebeverine in man. J Pharm Biomed Anal. 2002 Jun 20;29 (1-2) :335-40.