RG7109
RG7109 is an inhibitor of HCV NS5B polymerase. RG7109 has EC50 values of 1.1 nM and 1.0 nM for HCV GT-1a H77 and GT-1b Con1, respectively. RG7109 exhibits favorable pharmacokinetic properties and can be used in anti-HCV research[1].
Product Specifications
CAS Number
[1257830-82-2]
UNSPSC
12352005
Target
DNA/RNA Synthesis; HCV
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
CS(=O)(NC1=CC=C(C2=CC3=C(OC)C(C(C)(C)C)=CC(C4=CC=C(OC)NC4=O)=C3N=C2)C=C1)=O
Molecular Formula
C27H29N3O5S
Molecular Weight
507.60
References & Citations
[1]Talamas FX, et al. Discovery of N-[4-[6-tert-butyl-5-methoxy-8- (6-methoxy-2-oxo-1H-pyridin-3-yl) -3-quinolyl]phenyl]methanesulfonamide (RG7109), a potent inhibitor of the hepatitis C virus NS5B polymerase. J Med Chem. 2014 Mar 13;57 (5) :1914-31.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12730/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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