Guanabenz (hydrochloride) (Standard)

Guanabenz (hydrochloride) (Standard) is the analytical standard of Guanabenz (hydrochloride) . This product is intended for research and analytical applications. Guanabenz hydrochloride is an orally active α-2-adrenoceptor agonist. Guanabenz hydrochloride has antihypertensive effect and antiparasitic activity. Guanabenz hydrochloride interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz hydrochloride also is used for the research of high blood pressure[1][2][3].

Product Specifications

CAS Number

[23113-43-1]

UNSPSC

12352100

Target

Adrenergic Receptor; Parasite; Reference Standards

Related Pathways

Anti-infection; GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cardiovascular Disease; Cancer

Smiles

ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1.Cl

Molecular Formula

C8H9Cl3N4

Molecular Weight

267.55

References & Citations

[1]Christiane Neuber, et al. Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes. PLoS One. 2014 Jun 3;9 (6) :e98893.|[2]Jennifer Martynowicz, et al. Guanabenz Reverses a Key Behavioral Change Caused by Latent Toxoplasmosis in Mice by Reducing Neuroinflammation. mBio. 2019 Apr 30;10 (2) :e00381-19.|[3]T Baum, et al. Studies on the centrally mediated hypotensive activity of guanabenz. Eur J Pharmacol. 1976 May;37 (1) :31-44.