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Tiadenol

Tiadenol is an absorbable hypolipidemic agent. Tiadenol can effectively reduce triglycerides and decrease the level of apolipoprotein E in very low-density lipoproteins in hyperlipoproteinemia. Tiadenol causes hepatomegaly in rats and affects their hepatic lipid levels, cholesterol synthesis and absorption at high doses. Tiadenol can be used in the research of endocrine and metabolic diseases such as hyperlipidemia[1][2].

Product Specifications

CAS Number

6964-20-1

UNSPSC

12352100

Target

Apolipoprotein

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Endocrinology; Metabolic Disease

Smiles

OCCSCCCCCCCCCCSCCO

Molecular Formula

C14H30O2S2

Molecular Weight

294.52

References & Citations

[1]Kritchevsky D, et al. Influence of tiadenol, bis- (hydroxyethylthio) 1,10-decane, on cholesterol metabolism in rats. Pharmacol Res Commun. 1979 Nov;11 (10) :861-7.|[2]Franceschini G, et al. Pharmacological studies on tiadenol in type IV patients. Evidence for a mechanism of action different from other lipid-lowering drugs. Atherosclerosis. 1981 Nov-Dec;40 (3-4) :245-55.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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