Tiadenol
Tiadenol is an absorbable hypolipidemic agent. Tiadenol can effectively reduce triglycerides and decrease the level of apolipoprotein E in very low-density lipoproteins in hyperlipoproteinemia. Tiadenol causes hepatomegaly in rats and affects their hepatic lipid levels, cholesterol synthesis and absorption at high doses. Tiadenol can be used in the research of endocrine and metabolic diseases such as hyperlipidemia[1][2].
Product Specifications
CAS Number
[6964-20-1]
UNSPSC
12352100
Target
Apolipoprotein
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology; Metabolic Disease
Smiles
OCCSCCCCCCCCCCSCCO
Molecular Formula
C14H30O2S2
Molecular Weight
294.52
References & Citations
[1]Kritchevsky D, et al. Influence of tiadenol, bis- (hydroxyethylthio) 1,10-decane, on cholesterol metabolism in rats. Pharmacol Res Commun. 1979 Nov;11 (10) :861-7.|[2]Franceschini G, et al. Pharmacological studies on tiadenol in type IV patients. Evidence for a mechanism of action different from other lipid-lowering drugs. Atherosclerosis. 1981 Nov-Dec;40 (3-4) :245-55.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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