Anisodine

Anisodine (Daturamine) is a neuroprotective compound that reduces exacerbated M1, M2, M4, and M5 receptor expression in brain tissues under hypoxia/reoxygenation conditions. Anisodine inhibits calcium ion influx and reactive oxygen species (ROS) levels. Anisodine leads to decreased aspartate levels during hypoxia[1].

Product Specifications

CAS Number

[52646-92-1]

Product Name Alternative

Daturamine; α-Hydroxyscopolamine

UNSPSC

12352005

Target

Calcium Channel; mAChR; Reactive Oxygen Species (ROS)

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Field of Research

Neurological Disease

Smiles

CN1[C@@H](C[C@H](OC([C@@](O)(CO)C2=CC=CC=C2)=O)C[C@H]31)[C@H]4[C@@H]3O4

Molecular Formula

C17H21NO5

Molecular Weight

319.35

References & Citations

[1]Wan F, et al. Modulation of muscarinic receptors by anisodine hydrobromide in cerebral ischemia. Cell Mol Biol (Noisy-le-grand) . 2023 Nov 15;69 (11) :17-24.