HBF-0259 (Standard)
HBF-0259 (Standard) is the analytical standard of HBF-0259. This product is intended for research and analytical applications. HBF-0259 is a potent and selective inhibitor of hepatitis B virus (HBV) surface antigen (HBsAg) secretion, with an EC50 of 1.5 μM in HepG2.2.15 cells. HBF-0259 has no effect on HBV DNA synthesis[1][2].
Product Specifications
CAS Number
957011-15-3
UNSPSC
12352100
Target
HBV; Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
ClC1=CC=C(C2N=C3N(NN=N3)C(C4=C(F)C=CC=C4Cl)C2)C=C1
Molecular Formula
C16H12Cl2FN5
Molecular Weight
364.20
References & Citations
[1]Dougherty AM, et, al. A substituted tetrahydro-tetrazolo-pyrimidine is a specific and novel inhibitor of hepatitis B virus surface antigen secretion. Antimicrob Agents Chemother. 2007 Dec;51 (12) :4427-37.|[2]Yu W, et, al. Design, synthesis, and biological evaluation of triazolo-pyrimidine derivatives as novel inhibitors of hepatitis B virus surface antigen (HBsAg) secretion. J Med Chem. 2011 Aug 25;54 (16) :5660-70.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6325541-01 0.1 mL
NKX2-1, ID (NKX2-1, NKX2A, TITF1, TTF1, Homeobox protein Nkx-2.1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1) (MaxLight 750)
Sign In for Pricing
View Details MBS6325541-02 5x 0.1 mL
NKX2-1, ID (NKX2-1, NKX2A, TITF1, TTF1, Homeobox protein Nkx-2.1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1) (MaxLight 750)
Sign In for Pricing
View Details 
46688156 3x 1.0 µg DNA
TIAM1 CRISPR All-in-one AAV vector set (with saCas9)(Rat)
Sign In for Pricing
View Details 
TL501610V 500 µL Each
Padi3 Mouse shRNA Lentiviral Particle (Locus ID 18601)
Sign In for Pricing
View Details MBS7242276-01 48 Well
Guinea pig Acyl-CoA synthetase short-chain family member 3, mitochondrial (ACSS3) ELISA Kit
Sign In for Pricing
View Details MBS7242276-02 96 Well
Guinea pig Acyl-CoA synthetase short-chain family member 3, mitochondrial (ACSS3) ELISA Kit
Sign In for Pricing
View Details