Methylmalonyl-CoA (tetralithium)

Methylmalonyl-CoA (Methylmalonyl coenzyme A) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl-CoA tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12[1].

Product Specifications

CAS Number

[104809-02-1]

Product Name Alternative

Isosuccinyl coenzyme A (tetralithium) ; Methylmalonyl coenzyme (tetralithium)

UNSPSC

12352204

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Purity

Solubility

10 mM in DMSO

Smiles

O[C@H]([C@@H]1O[P](O[Li])(O[Li])=O)[C@](O[C@@H]1CO[P](O[P](OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(C(C)C(O)=O)=O)=O)=O)(O[Li])=O)(O[Li])=O)([H])N2C3=NC=NC(N)=C3N=C2

Molecular Formula

C25H36Li4N7O19P3S

Molecular Weight

891.34

Precautions

H315, H319, H335

References & Citations

[1]Gotoh K, et al. Assay for methylmalonyl coenzyme A mutase activity based on determination of succinyl coenzyme A by ultrahigh-performance liquid chromatography tandem mass spectrometry. Anal Bioanal Chem. 2015 Jul;407 (18) :5281-6.