(6R) -Leucovorin
(6R) -Leucovorin is a derivative of Folic Acid, a vitamin that plays a crucial role in DNA synthesis, DNA repair, and DNA methylation, and also serves as a cofactor in biological reactions involving folate[1][2].
Product Specifications
CAS Number
73951-54-9
Product Name Alternative
(6R) -Folinic acid
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative
Related Pathways
Others
Field of Research
Others
Smiles
O=C(CC[C@H](NC(C1=CC=C(C=C1)NC[C@H]2N(C3=C(NC2)NC(N)=NC3=O)C=O)=O)C(O)=O)O
Molecular Formula
C20H23N7O7
Molecular Weight
473.44
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Zittoun J, et al. Comparative effect of 6S, 6R and 6RS leucovorin on methotrexate rescue and on modulation of 5-fluorouracil. Br J Cancer. 1991 Jun;63 (6) :885-8.|[2]Liu K, et al. Simultaneous determination of 6R-leucovorin, 6S-leucovorin and 5-methyltetrahydrofolate in human plasma using solid phase extraction and chiral liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Apr 1;877 (10) :902-10.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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