(-) -Mitorubrinic acid
(-) -Mitorubrinic acid (Mitorubrinic acid) is a polyketide. (-) -Mitorubrinic acid is synthesis by two non-reducing polyketide synthase (PKS) genes (pks12 and pks11) in a sequential manner. (-) -Mitorubrinic is a virulence factor of Penicillium marneffei by improving its intracellular survival in macrophages[1].
Product Specifications
CAS Number
[58958-07-9]
Product Name Alternative
Mitorubrinic acid
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative; Fungal
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
O=C(O[C@]1(C)C(C2=COC(/C=C/C(O)=O)=CC2=CC1=O)=O)C3=C(C)C=C(O)C=C3O
Molecular Formula
C21H16O9
Molecular Weight
412.35
Precautions
P261-P280-P302+P352
References & Citations
[1]Woo PC, et al. First discovery of two polyketide synthase genes for mitorubrinic acid and mitorubrinol yellow pigment biosynthesis and implications in virulence of Penicillium marneffei. PLoS Negl Trop Dis. 2012;6 (10) :e1871.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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