MAI-400
MAI-400 is an APC-Asef interaction inhibitor (Kd = 12 nM, IC50 = 250 nM) . MAI-400 can be used in the research of colorectal cancer[1].
Product Specifications
CAS Number
2250328-65-3
UNSPSC
12352005
Target
APC
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(O)CC[C@@H](C(N)=O)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@@H](NC(CNC([C@@H](NC(OCC2=CC=CC=C2)=O)C)=O)=O)CCC(O)=O)=O)=O)=O)=O
Molecular Formula
C41H56N8O15
Molecular Weight
900.93
References & Citations
[1]Yang X, et al. Rational Design and Structure Validation of a Novel Peptide Inhibitor of the Adenomatous-Polyposis-Coli (APC) -Rho-Guanine-Nucleotide-Exchange-Factor-4 (Asef) Interaction. J Med Chem. 2018 Sep 13;61 (17) :8017-8028.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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